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Antikörper

GAD1 Antibody

Produktgrößen
100 ug
£582,00
OAAL00115-100UG
Über dieses Produkt
SKU:
OAAL00115
Zusätzliche Namen:
67 kDa glutamic acid decarboxylase;CPSQ1;DEE89;GAD;GAD-67;glutamate decarboxylase 1;glutamate decarboxylase 1 (brain; 67kDa);SCP.
Klonalität:
Monoclonal
Weitere Details:
This gene encodes one of several forms of glutamic acid decarboxylase; identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products; the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq
Gendetails:
glutamate decarboxylase 1
Host:
Mouse
Immunogen:
GAD1 (AAH37780; 1 a.a. ~ 594 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Isotyp:
IgG2a Kappa
Proteindetails:
Glutamate decarboxylase 1 (brain; 67kDa) [Homo sapiens]|Homo sapiens glutamate decarboxylase 1 (brain; 67kDa); mRNA (cDNA clone MGC:41888 IMAGE:5273792); complete cds
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody