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Antikörper

FDPS Antibody

Produktgrößen
100 ug
£582,00
OAAL00101-100UG
Über dieses Produkt
SKU:
OAAL00101
Zusätzliche Namen:
(2E;6E)-farnesyl diphosphate synthase;farnesyl pyrophosphate synthase;farnesyl pyrophosphate synthetase; dimethylallyltranstransferase; geranyltranstransferase;FPP synthase;FPP synthetase;FPPS;FPS;POROK9.
translate.label.attr.clone:
3A6
Klonalität:
Monoclonal
Weitere Details:
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product; farnesyl pyrophosphate; is a key intermediate in cholesterol and sterol biosynthesis; a substrate for protein farnesylation and geranylgeranylation; and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1; 7; 14; 15; 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene
Gendetails:
farnesyl diphosphate synthase
Host:
Mouse
Immunogen:
FDPS (NP_001995.1; 320 a.a. ~ 419 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Isotyp:
IgG2a Kappa
Proteindetails:
farnesyl pyrophosphate synthase isoform a [Homo sapiens]|Homo sapiens farnesyl diphosphate synthase (FDPS); transcript variant 1; mRNA
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody