ETF1 Antibody
Produktgrößen
100 ug
£582,00
OAAL00094-100UG
Über dieses Produkt
- SKU:
- OAAL00094
- Zusätzliche Namen:
- D5S1995;ERF;ERF1;eukaryotic peptide chain release factor subunit 1;polypeptide chain release factor 1;protein Cl1;RF1;sup45 (yeast omnipotent suppressor 45) homolog-like 1;SUP45L1;TB3-1.
- translate.label.attr.clone:
- 2H4
- Klonalität:
- Monoclonal
- Weitere Details:
- Termination of protein biosynthesis and release of the nascent polypeptide chain are signaled by the presence of an in-frame stop codon at the aminoacyl site of the ribosome. The process of translation termination is universal and is mediated by protein release factors (RFs) and GTP. A class 1 RF recognizes the stop codon and promotes the hydrolysis of the ester bond linking the polypeptide chain with the peptidyl site tRNA; a reaction catalyzed at the peptidyl transferase center of the ribosome. Class 2 RFs; which are not codon specific and do not recognize codons; stimulate class 1 RF activity and confer GTP dependency upon the process. In prokaryotes; both class 1 RFs; RF1 and RF2; recognize UAA; however; UAG and UGA are decoded specifically by RF1 and RF2; respectively. In eukaryotes; eRF1; or ETF1; the functional counterpart of RF1 and RF2; functions as an omnipotent RF; decoding all 3 stop codons (Frolova et al.; 1994 [PubMed 7990965]).[supplied by OMIM
- Gendetails:
- eukaryotic translation termination factor 1
- Host:
- Mouse
- Immunogen:
- ETF1 (NP_004721.1; 338 a.a. ~ 437 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotyp:
- IgG2b Kappa
- Proteindetails:
- eukaryotic peptide chain release factor subunit 1 isoform 1 [Homo sapiens]|Homo sapiens eukaryotic translation termination factor 1 (ETF1); transcript variant 1; mRNA
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php