E2F4 Antibody
Produktgrößen
100 ug
£582,00
OAAL00083-100UG
Über dieses Produkt
- SKU:
- OAAL00083
- Zusätzliche Namen:
- E2F transcription factor 4; p107/p130-binding;E2F-4;p107/p130-binding protein;transcription factor E2F4.
- translate.label.attr.clone:
- 5B7
- Klonalität:
- Monoclonal
- Weitere Details:
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain; a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP); a transactivation domain enriched in acidic amino acids; and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB; p107 and p130; but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes; and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq
- Gendetails:
- E2F transcription factor 4
- Host:
- Mouse
- Immunogen:
- E2F4 (NP_001941; 211 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotyp:
- IgG1 Kappa
- Proteindetails:
- Homo sapiens E2F transcription factor 4 (E2F4); mRNA|transcription factor E2F4 [Homo sapiens]
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php