DFFA Antibody
Produktgrößen
100 ug
£582,00
OAAL00071-100UG
Über dieses Produkt
- SKU:
- OAAL00071
- Zusätzliche Namen:
- DFF1;DFF45;DFF-45;DNA fragmentation factor 45 kDa subunit;DNA fragmentation factor subunit alpha;DNA fragmentation factor; 45kDa; alpha polypeptide;ICAD;inhibitor of CAD.
- translate.label.attr.clone:
- 3A11
- Klonalität:
- Monoclonal
- Weitere Details:
- Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB; the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
- Gendetails:
- DNA fragmentation factor subunit alpha
- Host:
- Mouse
- Immunogen:
- DFFA (NP_004392.1; 231 a.a. ~ 331 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotyp:
- IgG2a Kappa
- Proteindetails:
- DNA fragmentation factor subunit alpha isoform 1 [Homo sapiens]|Homo sapiens DNA fragmentation factor subunit alpha (DFFA); transcript variant 1; mRNA
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php