CREBL2 Antibody
Produktgrößen
100 ug
£582,00
OAAL00059-100UG
Über dieses Produkt
- SKU:
- OAAL00059
- Zusätzliche Namen:
- cAMP-responsive element-binding protein-like 2;MHBs-binding protein 1.
- translate.label.attr.clone:
- 1C1
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes; frequently associated with hematopoietic malignancies; as well as breast; non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding; followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq
- Gendetails:
- cAMP responsive element binding protein like 2
- Host:
- Mouse
- Immunogen:
- CREBL2 (NP_001301.1; 1 a.a. ~ 120 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotyp:
- IgG<sub>2a</sub> Kappa
- Proteindetails:
- cAMP-responsive element-binding protein-like 2 [Homo sapiens]|Homo sapiens cAMP responsive element binding protein like 2 (CREBL2); mRNA
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php