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Antikörper

CASP10 Antibody

Produktgrößen
100 ug
£582,00
OAAL00039-100UG
Über dieses Produkt
SKU:
OAAL00039
Zusätzliche Namen:
ALPS2;apoptotic protease MCH-4;CASP-10;caspase 10 apoptosis-related cysteine peptidase;caspase 10; apoptosis-related cysteine protease;caspase-10;FADD-like ICE2;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;FLICE-2;ICE-like apoptotic protease 4;interleukin-1B-converting enzyme 2;MCH4.
translate.label.attr.clone:
3C9
Klonalität:
Monoclonal
Weitere Details:
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7; and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Gendetails:
caspase 10
Host:
Mouse
Immunogen:
CASP10 (NP_116756.2; 19 a.a. ~ 187 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Isotyp:
IgG2a Kappa
Proteindetails:
caspase-10 isoform 2 preproprotein [Homo sapiens]|Homo sapiens caspase 10 (CASP10); transcript variant 2; mRNA
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody