CAMLG Antibody
Produktgrößen
100 ug
£582,00
OAAL00038-100UG
Über dieses Produkt
- SKU:
- OAAL00038
- Zusätzliche Namen:
- calcium signal-modulating cyclophilin ligand;calcium-modulating cyclophilin ligand;CAML;cyclophilin B-binding protein;GET2;guided entry of tail-anchored proteins factor CAMLG.
- translate.label.attr.clone:
- 3F12
- Klonalität:
- Monoclonal
- Weitere Details:
- The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B; cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A; binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway; implicating cyclophilin B in calcium signaling; even in the absence of cyclosporin. [provided by RefSeq
- Gendetails:
- calcium modulating ligand
- Host:
- Mouse
- Immunogen:
- CAMLG (NP_001736; 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotyp:
- IgG2b Kappa
- Proteindetails:
- calcium signal-modulating cyclophilin ligand [Homo sapiens]|Homo sapiens calcium modulating ligand (CAMLG); mRNA
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php