EED Antibody
Produktgrößen
100 uL
£446,00
OAAJ07774-100UL
Über dieses Produkt
- SKU:
- OAAJ07774
- Zusätzliche Namen:
- HEED; COGIS; WAIT1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/mL
- Weitere Details:
- Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex; which methylates 'Lys-9' and 'Lys-27' of histone H3; leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27'; whereas H3 'Lys-27' recognition has the opposite effect; enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases; thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8; HOXA9; MYT1 and CDKN2A.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human EED
- Molekulargewicht:
- 50 kDa
- Proteindetails:
- Polycomb protein EED
- Aufreinigung:
- Immunogen affinity chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php