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Antikörper

CUL5 Antibody

Produktgrößen
100 uL
£446,00
OAAJ07772-100UL
Über dieses Produkt
SKU:
OAAJ07772
Zusätzliche Namen:
CUL-5; VACM1; VACM-1
Klonalität:
Polyclonal
Konzentration:
1 mg/mL
Weitere Details:
Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes; which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
Host:
Rabbit
Immunogen:
Recombinant protein of human CUL5
Molekulargewicht:
91 kDa
Proteindetails:
Cullin-5
Aufreinigung:
Immunogen affinity chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody