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Antikörper

CLDN1 Antibody

Produktgrößen
100 uL
£446,00
OAAJ07393-100UL
Über dieses Produkt
SKU:
OAAJ07393
Zusätzliche Namen:
CLD1; SEMP1; ILVASC
Klonalität:
Polyclonal
Konzentration:
1 mg/mL
Weitere Details:
Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers; others mediate the permeability to ions and small molecules. Often; several claudin family members are coexpressed and interact with each other; and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin; probably via an indirect effect on the expression levels of other proteins; since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.
Host:
Rabbit
Immunogen:
Recombinant proteinof human CLDN1
Molekulargewicht:
23 kDa
Proteindetails:
Claudin-1
Aufreinigung:
Immunogen affinity chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody