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Antikörper

ANGPTL4 Antibody

Produktgrößen
100 uL
£446,00
OAAJ07225-100UL
Über dieses Produkt
SKU:
OAAJ07225
Zusätzliche Namen:
NL2; ARP4; FIAF; HARP; PGAR; HFARP; TGQTL; UNQ171; pp1158
Klonalität:
Polyclonal
Konzentration:
1 mg/mL
Weitere Details:
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation; migration; and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis; lipid metabolism; and insulin sensitivity. In response to hypoxia; the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation .
Host:
Rabbit
Immunogen:
Recombinant protein of human ANGPTL4
Molekulargewicht:
45 kDa
Proteindetails:
Angiopoietin-related protein 4
Aufreinigung:
Immunogen affinity chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody