DKC1 Antibody
Produktgrößen
100 uL
£446,00
OAAJ07140-100UL
Über dieses Produkt
- SKU:
- OAAJ07140
- Zusätzliche Namen:
- DKC; CBF5; DKCX; NAP57; NOLA4; XAP101
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/mL
- Weitere Details:
- Isoform 1: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex; which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5; instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues; which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC; the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. Isoform 3: Promotes cell to cell and cell to substratum adhesion; increases the cell proliferation rate and leads to cytokeratin hyper-expression (when overexpressed in HeLa cells).
- Host:
- Rabbit
- Immunogen:
- Recombinant proteinof human DKC1
- Molekulargewicht:
- 58 kDa
- Proteindetails:
- H/ACA ribonucleoprotein complex subunit 4
- Aufreinigung:
- Immunogen affinity chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php