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Antikörper

CXADR Antibody

Produktgrößen
100 uL
£446,00
OAAJ07112-100UL
Über dieses Produkt
SKU:
OAAJ07112
Zusätzliche Namen:
CAR; HCAR; CAR4/6
Klonalität:
Polyclonal
Konzentration:
1 mg/mL
Weitere Details:
Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells; a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding; JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
Host:
Rabbit
Immunogen:
Recombinant protein of human CXADR
Molekulargewicht:
40 kDa
Proteindetails:
Coxsackievirus and adenovirus receptor
Aufreinigung:
Immunogen affinity chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody