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Antikörper

FXN Antibody

Produktgrößen
100 uL
£446,00
OAAJ07064-100UL
Über dieses Produkt
SKU:
OAAJ07064
Zusätzliche Namen:
FA; X25; CyaY; FARR; FRDA
Klonalität:
Polyclonal
Konzentration:
1 mg/mL
Weitere Details:
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization; however; the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1.
Host:
Rabbit
Immunogen:
Recombinant proteinof human FXN
Molekulargewicht:
23 kDa
Proteindetails:
Frataxin; mitochondrial
Aufreinigung:
Immunogen affinity chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody