ATG4C Antibody
Produktgrößen
100 uL
£446,00
OAAJ06733-100UL
Über dieses Produkt
- SKU:
- OAAJ06733
- Zusätzliche Namen:
- APG4C; AUTL1; AUTL3; APG4-C
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/mL
- Weitere Details:
- Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation . Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2; to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes; which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
- Host:
- Rabbit
- Immunogen:
- Recombinant proteinof human ATG4C
- Molekulargewicht:
- 52 kDa
- Proteindetails:
- Cysteine protease ATG4C
- Aufreinigung:
- Immunogen affinity chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php