CCNC Antibody
Produktgrößen
100 uL
£446,00
OAAJ06415-100UL
Über dieses Produkt
- SKU:
- OAAJ06415
- Zusätzliche Namen:
- CycC; SRB11; hSRB11
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/mL
- Weitere Details:
- Component of the Mediator complex; a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II); which may inhibit the formation of a transcription initiation complex.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human Cyclin C (Phospho-Ser275)
- Molekulargewicht:
- 33 kDa
- Proteindetails:
- Cyclin-C
- Aufreinigung:
- Immunogen affinity chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php