EPHB4 Antibody
Produktgrößen
100 uL
£446,00
OAAJ06258-100UL
Über dieses Produkt
- SKU:
- OAAJ06258
- Zusätzliche Namen:
- HTK; MYK1; HFASD; CMAVM2; LMPHM7; TYRO11
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/mL
- Weitere Details:
- Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells; leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling; morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human EPHB4
- Molekulargewicht:
- 108 kDa
- Proteindetails:
- Ephrin type-B receptor 4
- Aufreinigung:
- Immunogen affinity chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php