FFAR4 Antibody
Produktgrößen
100 uL
£446,00
OAAJ06207-100UL
Über dieses Produkt
- SKU:
- OAAJ06207
- Zusätzliche Namen:
- GT01; PGR4; BMIQ10; GPR120; GPR129; O3FAR1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/mL
- Weitere Details:
- Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects; particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect; but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human GPR120; corresponding to a region within the internal amino acids.
- Molekulargewicht:
- 42 kDa
- Proteindetails:
- Free fatty acid receptor 4
- Aufreinigung:
- Purified by peptide affinity chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20°C. Stable for 12 months from date of receipt.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php