FZD1 Antibody
Produktgrößen
100 uL
£446,00
OAAJ05695-100UL
Über dieses Produkt
- SKU:
- OAAJ05695
- Zusätzliche Namen:
- DKFZp564G072; FLJ95923; Frizzled-1; Fz-1; FzE1; hFz1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/mL
- Weitere Details:
- Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway; which leads to the activation of disheveled proteins; inhibition of GSK-3 kinase; nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members; but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway; as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A; Wnt3; Wnt1 and to a lesser extent Wnt2; but not by Wnt4; Wnt5A; Wnt5B; Wnt6; Wnt7A or Wnt7B.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide
- Molekulargewicht:
- 71 kDa
- Proteindetails:
- Frizzled-1
- Aufreinigung:
- Immunogen affinity chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php