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Antikörper

ERI1 Antibody

Produktgrößen
100 uL
£446,00
OAAJ05675-100UL
Über dieses Produkt
SKU:
OAAJ05675
Zusätzliche Namen:
HEXO; THEX1; 3'HEXO
Klonalität:
Polyclonal
Konzentration:
1 mg/mL
Weitere Details:
RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them; suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro; suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Host:
Rabbit
Immunogen:
A synthesized peptide
Molekulargewicht:
40 kDa
Proteindetails:
3'-5' exoribonuclease 1
Aufreinigung:
Immunogen affinity chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody