APOBEC3D/F Antibody
Produktgrößen
100 uL
£446,00
OAAJ05223-100UL
Über dieses Produkt
- SKU:
- OAAJ05223
- Zusätzliche Namen:
- APOBEC3DE; APOBEC3E; ARP6
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/mL
- Weitere Details:
- DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription; it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA; leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome; along with a deamination-independent mechanism that works prior to the proviral integration; together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide
- Molekulargewicht:
- 40 kDa
- Proteindetails:
- DNA dC->dU-editing enzyme APOBEC-3D
- Aufreinigung:
- Immunogen affinity chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php