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Antikörper

EZH1 Antibody

Produktgrößen
100 uL
£446,00
OAAJ04277-100UL
Über dieses Produkt
SKU:
OAAJ04277
Zusätzliche Namen:
KMT6B
Klonalität:
Polyclonal
Konzentration:
1 mg/mL
Weitere Details:
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex; which methylates 'Lys-27' of histone H3; leading to transcriptional repression of the affected target gene. Able to mono-; di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1; H3K27me2 and H3K27me3; respectively. Required for embryonic stem cell derivation and self-renewal; suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes; it is less abundant in embryonic stem cells; has weak methyltransferase activity and plays a less critical role in forming H3K27me3; which is required for embryonic stem cell identity and proper differentiation.
Host:
Rabbit
Immunogen:
A synthesized peptide
Molekulargewicht:
85 kDa
Proteindetails:
Histone-lysine N-methyltransferase EZH1
Aufreinigung:
Immunogen affinity chromatography
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody