CUL2 Antibody
Produktgrößen
100 ul
£446,00
OAAJ01740-100UL
Über dieses Produkt
- SKU:
- OAAJ01740
- Zusätzliche Namen:
- CUL-2; CUL2; cullin 2; Cullin-2; MGC131970
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CUL2 Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes; which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).
- Gendetails:
- cullin 2
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human Cullin 2
- Molekulargewicht:
- 82 kDa; 84 kDa
- Aufreinigung:
- Affinity-chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Stable for 12 months from date of receipt.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php