CDH1 Antibody
Produktgrößen
100 ul
£446,00
OAAJ01730-100UL
Über dieses Produkt
- SKU:
- OAAJ01730
- Zusätzliche Namen:
- UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CDH1 a single-pass type I membrane protein; and calcium dependent cell adhesion proteins. It is a ligand for integrin alpha-E/beta-7; and it colocalizes with DLG7 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-; beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx; results in translocation from sites of cell-cell contact to the cytoplasm. Involved in mechanisms regulating cell-cell adhesions; mobility and proliferation of epithelial cells. Defects in CDH1 are involved in dysfunction of the cell-cell adhesion system; triggering cancer invasion (gastric; breast; ovary; endometrium and thyroid) and metastasis.
- Gendetails:
- cadherin 1; type 1
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human E-cadherin
- Molekulargewicht:
- 120 kDa
- Aufreinigung:
- Affinity-chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Stable for 12 months from date of receipt.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php