Anti-Cit-Histone H3 Antibody
Produktgrößen
100ug
£619,00
OAAI00794-100UG
Über dieses Produkt
- SKU:
- OAAI00794
- Zusätzliche Namen:
- H3 histone family; member A;H3/A;H3C10;H3C11;H3C12;H3C2;H3C3;H3C4;H3C6;H3C7;H3C8;H3FA;HIST1H3A;histone 1; H3a;histone cluster 1 H3 family member a;histone cluster 1; H3a;histone H3.1;histone H3/a.
- Klonalität:
- Polyclonal
- Konzentration:
- 100ug/200ul
- Weitere Details:
- Histones are basic nuclear proteins that together with DNA make up the nucleosome structure in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A; H2B; H3; and H4). The methylation of specific residues in the histone tails is a central modification for regulatingepigenetic transitions in chromatin. Whereas methylation of histone H3 on lysine 4; 36; and 79 has been linked with gene activation; methylation of H3 on lysines 9; 27 and histone H4 on lysine 20 is associated with heterochromatin and some repressed genes with euchromatin. Modified lysine residues can exist in a mono-; di-; or tri-methylated state; while the arginine residues can be mono- or di-methylated. Histone H3 Lys4 trimethylation (H3-K4me3) is a conserved mark of actively transcribed chromatin. This Antibody is specific for histone H3 tri-methylated at K27. The sequence is found in all mammals and a wide range of species; including D. melanogaster; Arabidopsis; Chicken and Xenopus. The Antibody will react with any of the above species where the trimethylation modification is present.
- Gendetails:
- H3 clustered histone 1
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide containing N-terminus of human histone H3 with citrulline modification at 2/8/17.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php