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Antikörper

Anti-Mon1b/SAND2 Polyclonal Antibody

Produktgrößen
100ug
£457,00
OAAI00791-100UG
Über dieses Produkt
SKU:
OAAI00791
Zusätzliche Namen:
HSRG1;HSV-1 stimulation-related gene 1 protein;HSV-I stimulating-related protein;MON1 secretory trafficking family member B;SAND2;SRG1;vacuolar fusion protein MON1 homolog B.
Klonalität:
Polyclonal
Konzentration:
100ug/200ul
Weitere Details:
SAND-1 (Mon1a (490aa) and Mon1b (547aa)) and CCZ-1 (Ccz1) are new factors for the apoptotic cells removal. Impaired apoptotic cell clearance (due to defective recognition; internalization or degradation) results in autoimmune disease. Mon1a and Mon1b; are similarly required for phagosome matuRation. Mon1a and Mon1b are required for phagosome matuRation.
Mona and its partner CCZ-1 form a complex (but not either protein alone) could bind small GTPase Rab7; thus influence Rab7 activation; Mon1a; Mon1b and CCZ-1 are critical and evolutionarily conserved components regulating the processing of ingested apoptotic cell corpses.
Gendetails:
MON1 homolog B; secretory trafficking associated
Host:
Rabbit
Immunogen:
A synthetic peptide derived from a portion of the intra domain 510-547aa of human Mon1b protein. This sequence is identical to human; mouse; rat; bovine and chicken.
Isotyp:
Rabbit IgG
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody