Anti-CCR9 Monoclonal Antibody
Produktgrößen
100ug
£532,00
OAAI00684-100UG
Über dieses Produkt
- SKU:
- OAAI00684
- Zusätzliche Namen:
- C-C chemokine receptor type 9;CC-CKR-9;CDw199;chemokine (C-C motif) receptor 9;G protein-coupled receptor 28;GPR28;GPR-9-6.
- translate.label.attr.clone:
- 3C3
- Klonalität:
- Monoclonal
- Konzentration:
- 100ug/200ul
- Weitere Details:
- CCR9; or C-C Motif Chemokine receptor type 9; is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migRation and matuRation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon; sμggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been found on lymphoid cells in both constitutively and in inflammation. It occurs on T lymphocytes of the small intestine; thymus; lymph node and spleen. CCR9 has mainly been reported to function in lymphocyte migRation althoμgh other cell types; such as tumor cells; can express CCR9; playing a role in prostate cancer cell migRation and invasion.
- Gendetails:
- C-C motif chemokine receptor 9
- Host:
- Mouse
- Immunogen:
- A synthetic peptide derived from N-terminus of the extracellular domain of human CCR9 protein.
- Isotyp:
- Mouse IgG2b
- Aufreinigung:
- The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php