Anti-Connexin 43 Antibody
Produktgrößen
100ug
£532,00
OAAI00634-100UG
Über dieses Produkt
- SKU:
- OAAI00634
- Zusätzliche Namen:
- AVSD3;CMDR;connexin-43;CX43;EKVP;EKVP3;gap junction 43 kDa heart protein;gap junction alpha-1 protein;gap junction protein; alpha 1; 43kDa;GJAL;HLHS1;HSS;ODDD;PPKCA.
- Klonalität:
- Polyclonal
- Konzentration:
- 100ug/200ul
- Weitere Details:
- Gap junction proteins allow the intercellular communication among adjacent cells by passing throμgh small molecules less than 1kDa. It is very important in regulating embryonic development; excitable cell contraction; tissue homeostasis; and normal cell growth and differentiation. Gap junctions are composed of integral membrane proteins from the connexin gene family.
Approximately 20 members have been cloned and characterized in Humans. During intercellular channel formation; six connexin proteins oligomerize into a hemi-channel or connexon followed by connexon trafficking to the plasma membrane.
The intact channel is formed when one hemi-channel docks with a second in an opposing cell. Once assembled; groups of these intercellular channels (termed gap junctional plaques) mediate the passage of amino acids; second messengers; and other metabolites between the connected cytoplasmic domains. The channels can be gated in response to various stimuli; including changes in voltage; pH; and connexin phosphorylation. Regulation of gap junctional communication could occur by controlling any one of the steps mentioned above. Phosphorylation of members of the connexin family of gap junction proteins has been correlated with gap junction assembly. - Gendetails:
- gap junction protein alpha 1
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to the C-terminal region with a phosphorylated Serine368 of human Connexin 43
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php