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Antikörper

Anti-Saposin Antibody

Produktgrößen
100ug
£424,00
OAAI00406-100UG
Über dieses Produkt
SKU:
OAAI00406
Zusätzliche Namen:
GLBA;PARK24;proactivator polypeptide;prosaposin;PSAPD;SAP1;SAP2;saposin-A;saposin-B;saposin-C;saposin-D;sphingolipid activator protein-1;sphingolipid activator protein-2.
Klonalität:
Polyclonal
Konzentration:
Varies by lot. See vial for concentration.
Weitere Details:
The Saposin family includes four structurally related proteins; saposin A; B; C; and D which are ~80 aa small acidic acitvator proteins with specificities for glycosphingolipid (GSL) hydrolases. They are derived from a single precursor; prosaposin.
In both Humans and mice; prosaposin/saposin deficiencies lead to severe neurological deficits. Saposins are processed from prosaposin in the late endosome and lysosome; and their stability is maintained by three disulfide bridges. The post-modified prosoposin is an ~70 kDa form which subsequently undergoes partial proteolysis to produce saposin A; B; C; and D; each proteins are between 12-14 kDa in mass.
Gendetails:
prosaposin
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to internal sequence (within 300-360aa) of human Saposin.
Isotyp:
Rabbit IgG
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
The antibodies are stable for 24 months from date of receipt when stored at -20°C to -70°C. The antibodies can be stored at 2-8°C for three months without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody