Anti-BCAR3 Antibody
Produktgrößen
100ug
£500,00
OAAI00368-100UG
Über dieses Produkt
- SKU:
- OAAI00368
- Zusätzliche Namen:
- AND-34;BCAR3; NSP family adaptor protein;breast cancer anti-estrogen resistance 3;breast cancer antiestrogen resistance 3 protein;breast cancer anti-estrogen resistance protein 3;dJ1033H22.2 (breast cancer anti-estrogen resistance 3);epididymis secretory sperm binding protein;mig-7;MIG7;migration inducting gene-7;novel SH2-containing protein 2;NSP2;SH2 domain-containing protein 3B;SH2D3B.
- Klonalität:
- Polyclonal
- Konzentration:
- 100ug/200ul
- Weitere Details:
- Breast cancer anti-estrogen resistance 3 (BCAR3) is a also known as AND-34/BCAR3/NSP2 (BCAR3). Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen.
However; breast cancers progress to become anti-estrogen resistant. BCAR3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent prolifeRation in Human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain; a hall mark of cellular tyrosine kinase signaling molecules; and is partly homologous to the cell division cycle protein CDC48 - Gendetails:
- BCAR3 adaptor protein; NSP family member
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide surrounding of -DRTPE- of human BCAR3 protein WITHOUT any phosphorylation site. This sequence is identical to human; rat; mouse; canis and bovine.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php