Anti-PKC Antibody
Produktgrößen
100ug
£457,00
OAAI00344-100UG
Über dieses Produkt
- SKU:
- OAAI00344
- Zusätzliche Namen:
- AAG6;aging-associated gene 6;PKCA;PKC-A;PKCalpha;PKC-alpha;PKCI+/-;PRKACA;protein kinase C alpha type.
- Klonalität:
- Polyclonal
- Konzentration:
- 100ug/200ul
- Weitere Details:
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. With cytotoxic dose (100 uM) of anticancer drμg; cisdiamminedlchloroplatinum(ll) (CDDP) incubation; the phosphorylation and translocation into nuclear of PKC in cancer cells including SKBR-3 which express different PKC isoforms was found. Overexpression of PKC was reported in several hemopoietic cell lines and tumors. PKC-epsilon was considered as a full oncogenic potential.
- Gendetails:
- protein kinase C alpha
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to the epitope -EDR-S-KSAP- with a phosphorylated Ser 345 of human PKC.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php