Anti-CD40 Antibody
Produktgrößen
100ug
£532,00
OAAI00212-100UG
Über dieses Produkt
- SKU:
- OAAI00212
- Zusätzliche Namen:
- B cell surface antigen CD40;B cell-associated molecule;Bp50;CD40 molecule; TNF receptor superfamily member 5;CD40L receptor;CDW40;p50;TNFRSF5;tumor necrosis factor receptor superfamily member 5.
- Klonalität:
- Polyclonal
- Konzentration:
- 100ug/200ul
- Weitere Details:
- The CD40 is a member of the TNF-receptor superfamily. It is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T-cell dependent immunoglobulin class switching; memory B cell development; and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand; which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation; and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). CD40 is a B cell surface antigen.
- Gendetails:
- CD40 molecule
- Host:
- Rabbit
- Immunogen:
- A Synthetic peptide QPVTQEDGKESRISVQERQ derived from human CD40 (258-277aa) was used as an immunogen.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php