Anti-CD29/INTEGRIN BETA 1 Antibody
Produktgrößen
100ug
£608,00
OAAI00114-100UG
Über dieses Produkt
- SKU:
- OAAI00114
- Zusätzliche Namen:
- CD29;FNRB;glycoprotein IIa;GPIIA;integrin beta 1;integrin beta-1;integrin VLA-4 beta subunit;integrin; beta 1 (fibronectin receptor; beta polypeptide; antigen CD29 includes MDF2; MSK12);MDF2;MSK12;very late activation protein; beta polypeptide;VLAB;VLA-BETA.
- Klonalität:
- Polyclonal
- Konzentration:
- 100ug/200ul
- Weitere Details:
- Integrin beta 1; also known as CD29; is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits (including alpha 1; alpha 2; alpha 3; alpha 4; alpha 5; and alpha 6; also known as CD49a; CD49b; CD49c; CD49d; CD49e; and CD49f; respectively) to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions; including embryonic development; wound repair; hemostasis; and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis; tumor cell growth; and metastasis. These heterodimeric receptors bridge the cytoplasmic actin cytoskeleton with proteins present in the extracellular matrix and/or on adjacent cells. The clustering of integrins on a cell surface leads to the formation of focal contacts. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression.
- Gendetails:
- integrin subunit beta 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encoding aa 579-799 of human CD29 expressed in E.Coli.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php