CLDN18 Antibody
Produktgrößen
50ul
£359,00
OAAF08291-50UL
100ul
£496,00
OAAF08291-100UL
Über dieses Produkt
- SKU:
- OAAF08291
- Zusätzliche Namen:
- SFTA5; SFTPJ
- translate.label.attr.clone:
- ABT-CLD18
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets; and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
- Gendetails:
- claudin 18
- Host:
- Mouse
- Immunogen:
- The antiserum was produced against synthesized peptide derived between 220-261 aa of human CLDN18. The exact sequence is proprietary.
- Isotyp:
- IgG
- Molekulargewicht:
- 28Â kDa
- Proteindetails:
- claudin-18
- Aufreinigung:
- Immunogen affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Shipped at 4C. Store at -20C. Stable for 12 months at -20C.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php