CBP Antibody
Produktgrößen
100 ug
£496,00
OAAF08208-100UG
Über dieses Produkt
- SKU:
- OAAF08208
- Zusätzliche Namen:
- CBP;CREB-binding protein;histone lysine acetyltransferase CREBBP;KAT3A;MKHK1;protein-lysine acetyltransferase CREBBP;RSTS;RSTS1.
- Klonalität:
- Polyclonal
- Konzentration:
- 1mg/ml
- Weitere Details:
- Acetylates histones; giving a specific tag for transcriptional activation. Also acetylates non-histone proteins; like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).
- Gendetails:
- CREB binding protein
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CBP.
- Molekulargewicht:
- 265 kDa
- Proteindetails:
- CREB-binding protein
- Aufreinigung:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php