ARHGDIA Antibody
Produktgrößen
100 ug
£496,00
OAAF07880-100UG
Über dieses Produkt
- SKU:
- OAAF07880
- Zusätzliche Namen:
- epididymis secretory sperm binding protein Li 47e;GDIA1;GDP-dissociation inhibitor; aplysia RAS-related 1;HEL-S-47e;NPHS8;Rho GDP dissociation inhibitor (GDI) alpha;rho GDP-dissociation inhibitor 1;RHOGDI;Rho-GDI alpha;RHOGDI-1.
- Klonalität:
- Polyclonal
- Konzentration:
- 1mg/ml
- Weitere Details:
- Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them; and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42; RAC1 and RHOA in an inactive cytosolic pool; regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell; mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins; may play a role in cell motility regulation. In glioma cells; inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1.
- Gendetails:
- Rho GDP dissociation inhibitor alpha
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ARHGDIA.
- Molekulargewicht:
- 23 kDa
- Proteindetails:
- Rho GDP-dissociation inhibitor 1
- Aufreinigung:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php