Bax Antibody
Produktgrößen
100 ug
£496,00
OAAF07835-100UG
Über dieses Produkt
- SKU:
- OAAF07835
- Zusätzliche Namen:
- apoptosis regulator BAX;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;BCL2 associated X protein;BCL2-associated X protein omega;bcl2-L-4;BCL2L4;bcl-2-like protein 4.
- Klonalität:
- Polyclonal
- Konzentration:
- 1mg/ml
- Weitere Details:
- Plays a role in the mitochondrial apoptotic process. Under normal conditions; BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL; which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM) (PubMed:21458670). Under stress conditions; undergoes a conformation change that causes translocation to the mitochondrion membrane; leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3; and thereby apoptosis.
- Gendetails:
- BCL2 associated X; apoptosis regulator
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Ser184.
- Molekulargewicht:
- 21 kDa
- Proteindetails:
- Apoptosis regulator BAX
- Aufreinigung:
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php