GATA4 Antibody
Produktgrößen
100 ug
£496,00
OAAF07566-100UG
Über dieses Produkt
- SKU:
- OAAF07566
- Zusätzliche Namen:
- ASD2;GATA-binding factor 4;TACHD;TOF;transcription factor GATA-4;VSD1.
- Klonalität:
- Polyclonal
- Konzentration:
- 1mg/ml
- Weitere Details:
- Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169; PubMed:27984724). In cooperation with TBX5; it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression; while it downregulates endocardial and endothelial gene expression (PubMed:27984724). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement (PubMed:20081228). Required during testicular development (PubMed:21220346). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme; spingosine-1-phosphate lyase (PubMed:15734735).
- Gendetails:
- GATA binding protein 4
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GATA4 around the phosphorylation site of Ser105.
- Molekulargewicht:
- 44 kDa
- Proteindetails:
- Transcription factor GATA-4
- Aufreinigung:
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php