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Antikörper

FAS Antibody

Produktgrößen
100 ug
£496,00
OAAF07562-100UG
Über dieses Produkt
SKU:
OAAF07562
Zusätzliche Namen:
ALPS1A;APO-1;Apo-1 antigen;APO-1 cell surface antigen;apoptosis antigen 1;apoptosis signaling receptor FAS;apoptosis-mediating surface antigen FAS;APT1;CD95;CD95 antigen;Fas (TNF receptor superfamily; member 6);Fas AMA;FAS1;FASLG receptor;FASTM;mutant tumor necrosis receptor superfamily member 6;TNF receptor superfamily member 6;TNFRSF6;tumor necrosis factor receptor superfamily member 6;tumor necrosis factor receptor superfamily; member 6.
Klonalität:
Polyclonal
Konzentration:
1mg/ml
Weitere Details:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance; in the antigen-stimulated suicide of mature T-cells; or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Gendetails:
Fas cell surface death receptor
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human FAS around the phosphorylation site of Tyr291.
Molekulargewicht:
37 kDa
Proteindetails:
Tumor necrosis factor receptor superfamily member 6
Aufreinigung:
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody