DAPK2 Antibody
Produktgrößen
100 ug
£496,00
OAAF07541-100UG
Über dieses Produkt
- SKU:
- OAAF07541
- Zusätzliche Namen:
- DAP kinase 2;DAP-kinase-related protein 1;death-associated protein kinase 2;DRP1;DRP-1.
- Klonalität:
- Polyclonal
- Konzentration:
- 1mg/ml
- Weitere Details:
- Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival; apoptosis; and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals; depending on the cellular setting. The former is caspase-dependent; while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).
- Gendetails:
- death associated protein kinase 2
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human DAPK2 around the phosphorylation site of Ser318.
- Molekulargewicht:
- 42 kDa
- Proteindetails:
- Death-associated protein kinase 2
- Aufreinigung:
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php