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Antikörper

BCL-2 Antibody

Produktgrößen
100 ug
£496,00
OAAF07514-100UG
Über dieses Produkt
SKU:
OAAF07514
Zusätzliche Namen:
apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;MPPH;MPPH2;PKB gamma;PKBG;PKB-GAMMA;PPP1R50;PRKBG;protein phosphatase 1; regulatory subunit 50;RAC-gamma;RAC-gamma serine/threonine protein kinase;RAC-gamma serine/threonine-protein kinase;RAC-PK-gamma;STK-2;v-akt murine thymoma viral oncogene homolog 3 (protein kinase B; gamma).
Klonalität:
Polyclonal
Konzentration:
1mg/ml
Weitere Details:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation; hence CASP1 activation and IL1B release (PubMed:17418785).
Gendetails:
AKT serine/threonine kinase 3|BCL2 apoptosis regulator
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human BCL-2 around the phosphorylation site of Thr69.
Molekulargewicht:
26 kDa
Proteindetails:
Apoptosis regulator Bcl-2
Aufreinigung:
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody