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Antikörper

GPR56 Antibody

Produktgrößen
100 ug
£496,00
OAAF04956-100UG
Über dieses Produkt
SKU:
OAAF04956
Zusätzliche Namen:
7-transmembrane protein with no EGF-like N-terminal domains-1;adhesion G-protein coupled receptor G1;BFPP;BPPR;G protein-coupled receptor 56;GPR56;G-protein coupled receptor 56;Protein TM7XN1;testicular tissue protein Li 77;TM7LN4;TM7XN1.
Klonalität:
Polyclonal
Weitere Details:
Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development; specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662). Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity). Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564; PubMed:21724588). Plays an essential role in testis development (By similarity).
Gendetails:
adhesion G protein-coupled receptor G1
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human GPR56.
Molekulargewicht:
77 kDa
Proteindetails:
Adhesion G-protein coupled receptor G1
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody