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Antikörper

FFAR1 Antibody

Produktgrößen
100 ug
£496,00
OAAF04881-100UG
Über dieses Produkt
SKU:
OAAF04881
Zusätzliche Namen:
FFA1R;free fatty acid receptor 1;GPCR40;GPR40;G-protein coupled receptor 40.
Klonalität:
Polyclonal
Weitere Details:
G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion; and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C; leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.
Gendetails:
free fatty acid receptor 1
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human FFAR1.
Molekulargewicht:
31 kDa
Proteindetails:
Free fatty acid receptor 1
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody