FFAR4 Antibody
Produktgrößen
100 ug
£496,00
OAAF04833-100UG
Über dieses Produkt
- SKU:
- OAAF04833
- Zusätzliche Namen:
- BMIQ10;free fatty acid receptor 4;GPR120;GPR129;G-protein coupled receptor 120;G-protein coupled receptor 129;G-protein coupled receptor GT01;G-protein coupled receptor PGR4;GT01;O3FAR1;omega-3 fatty acid receptor 1;PGR4.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects; particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect; but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.
- Gendetails:
- free fatty acid receptor 4
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GPR120.
- Isotyp:
- IgG
- Molekulargewicht:
- 42 kDa
- Proteindetails:
- Free fatty acid receptor 4
- Aufreinigung:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php