FZD9 Antibody
Produktgrößen
100 ug
£496,00
OAAF04822-100UG
Über dieses Produkt
- SKU:
- OAAF04822
- Zusätzliche Namen:
- CD349;frizzled 9; seven transmembrane spanning receptor;frizzled family receptor 9;frizzled homolog 9;frizzled-9;fz-9;FZD3;fzE6;hFz9.
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway; which leads to the activation of disheveled proteins; inhibition of GSK-3 kinase; nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity). Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway (By similarity). May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process (PubMed:27509850). During hippocampal development; regulates neuroblast proliferation and apoptotic cell death. Controls bone formation through non canonical Wnt signaling mediated via ISG15. Positively regulates bone regeneration through non canonical Wnt signaling (By similarity).
- Gendetails:
- frizzled class receptor 9
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human FZD9.
- Isotyp:
- IgG
- Molekulargewicht:
- 64 kDa
- Proteindetails:
- Frizzled-9
- Aufreinigung:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php