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Antikörper

APLNR Antibody

Produktgrößen
100 ug
£496,00
OAAF04771-100UG
Über dieses Produkt
SKU:
OAAF04771
Zusätzliche Namen:
AGTRL1;angiotensin II receptor-like 1;angiotensin receptor-like 1;apelin receptor;APJ;APJ (apelin) receptor;APJ receptor;APJR;G protein-coupled receptor APJ;G-protein coupled receptor APJ;G-protein coupled receptor HG11;HG11;HG11 orphan receptor.
Klonalität:
Polyclonal
Weitere Details:
Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:11090199; PubMed:25639753; PubMed:28137936). Plays a key role in early development such as gastrulation; blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone (By similarity). May promote angioblast migration toward the embryonic midline; i.e. the position of the future vessel formation; during vasculogenesis (By similarity). Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development (By similarity). Plays also a role in various processes in adults such as regulation of blood vessel formation; blood pressure; heart contractility and heart failure (PubMed:25639753; PubMed:28137936).
Gendetails:
apelin receptor
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human AGTRL1.
Molekulargewicht:
42 kDa
Proteindetails:
Apelin receptor
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody