CREB3L2 Antibody
Produktgrößen
100 ug
£496,00
OAAF04514-100UG
Über dieses Produkt
- SKU:
- OAAF04514
- Zusätzliche Namen:
- basic transcription factor 2;BBF2 human homolog on chromosome 7;BBF2H7;B-ZIB transcription factor;cAMP-responsive element-binding protein 3-like protein 2;cyclic AMP-responsive element-binding protein 3-like protein 2;FUS/BBF2H7 protein;TCAG_1951439.
- Klonalität:
- Polyclonal
- Weitere Details:
- Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress; inserted into ER membranes; with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress; transported to the Golgi; where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A; which promotes the transport and secretion of cartilage matrix proteins; and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line; protects cells from ER stress-induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827).
- Gendetails:
- cAMP responsive element binding protein 3 like 2
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CREB3L2.
- Isotyp:
- IgG
- Molekulargewicht:
- 57 kDa
- Proteindetails:
- Cyclic AMP-responsive element-binding protein 3-like protein 2
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php