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Antikörper

ELL2 Antibody

Produktgrößen
100 ug
£496,00
OAAF04213-100UG
Über dieses Produkt
SKU:
OAAF04213
Zusätzliche Namen:
ELL-related RNA polymerase II; elongation factor;elongation factor RNA for polymerase II 2;elongation factor; RNA polymerase II; 2;metastatic renal cell carcinoma-associated transcript 1;MRCCAT1;RNA polymerase II elongation factor ELL2.
Klonalität:
Polyclonal
Weitere Details:
Elongation factor component of the super elongation complex (SEC); a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC); a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing; influencing both proximal poly(A) site choice and exon skipping; as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane-specific to secretory IgH mRNA expression.
Gendetails:
elongation factor for RNA polymerase II 2
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human ELL2.
Molekulargewicht:
72 kDa
Proteindetails:
RNA polymerase II elongation factor ELL2
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody