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Antikörper

ARHGEF5 Antibody

Produktgrößen
100 ug
£496,00
OAAF04193-100UG
Über dieses Produkt
SKU:
OAAF04193
Zusätzliche Namen:
ephexin3;ephexin-3;GEF5;guanine nucleotide regulatory protein TIM;oncogene TIM;P60;p60 TIM;Rho guanine nucleotide exchange factor (GEF) 5;rho guanine nucleotide exchange factor 5;TIM;TIM1;transforming immortalized mammary oncogene.
Klonalität:
Polyclonal
Weitere Details:
Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB; weakly activates RHOC and RHOG and shows no effect on RHOD; RHOV; RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).
Gendetails:
Rho guanine nucleotide exchange factor 5
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human ARHGEF5.
Molekulargewicht:
60 kDa
Proteindetails:
Rho guanine nucleotide exchange factor 5
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody